A few Scientific Foundations Behind Callie

1. Individual Alpha Frequency (IAF)

Each patient’s baseline alpha peak is estimated so frequency bands are individualized rather than based on population norms.

Why this matters:

→ Ensures all session comparisons are anchored to the individual, not averages.

https://www.mdpi.com/2313-7673/10/11/730?utm_

2. Frontal Theta/Alpha Log Ratio

The log transformed ratio of frontal theta and alpha power is computed across the session.

Why this matters:

→ Provides a stable marker of relative cognitive effort and engagement over time.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9149374/?utm_

3. Occipital Alpha Calculated

Relative changes in occipital alpha power are examined across the session.

Why this matters:

→ Helps contextualize shifts in attentional orientation without labeling internal states.

https://www.sciencedirect.com/science/article/abs/pii/S0006899322002189?utm_

4. Z-score Normalization

All spectral features are normalized within the individual using baseline statistics.

Why this matters:

→ Allows session changes to be interpreted as deviations from that person’s typical state.

https://www.researchgate.net/publication/397230750_Mapping_EEG_Metrics_to_Human_Affective_and_Cognitive_Models_An_Interdisciplinary_Scoping_Review_from_a_Cognitive_Neuroscience_Perspective?utm_

5. Theta & Alpha Related studies

https://pmc.ncbi.nlm.nih.gov/articles/PMC9149374/

https://pmc.ncbi.nlm.nih.gov/articles/PMC6614966/